Site-specific cross-linking of collagen peptides by lysyl advanced glycation endproducts.
نویسندگان
چکیده
Cross-linking of proteins by advanced glycation endproducts (AGEs) causes a host of pathological conditions but their exact roles are unknown. Cross-linking lysyl AGEs were synthesized and incorporated into two types of collagen peptides. The utility of these cross-linked peptides for biochemical investigations was demonstrated by proteolysis studies and circular dichroism.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 38 شماره
صفحات -
تاریخ انتشار 2014